For severe acne, particularly cystic or nodular types unresponsive to typical topical and oral acne medications, our dermatologists may recommend isotretinoin. This prescription medication is a potent option for tackling resistant acne, providing an alternative when other treatments have failed.

Offered at MOD Dermatology near Papillion, isotretinoin acne treatment involves detailed guidance from our dermatologists on safe usage and potential side effects. This approach aims to achieve lasting clear skin for those struggling with severe acne, making isotretinoin a vital option in comprehensive acne care.


Isotretinoin is an oral medication requiring a prescription. It uniquely combats the four leading causes of acne: excessive oil production, bacteria P. acne, blocked pores, and inflammation. Understanding these triggers is crucial for anyone interested in choosing our clinic near Papillion for isotretinoin acne treatment.


Our body produces sebum to moisturize hair and skin. Sometimes, too much sebum leads to trapped skin cells in pores, causing them to clog. These clogged pores can become inflamed due to bacteria on the skin, resulting in acne. Isotretinoin addresses these issues, including:

  • Excess Sebum Production: Isotretinoin makes the oil glands smaller, leading to less sebum (oil) being produced. This action helps in avoiding clogged pores and stops acne from forming.
  • Bacteria P. Acne: Isotretinoin aids in controlling bacteria P. acnes because bacteria plays a major role in causing acne. By cutting down on these bacteria, isotretinoin reduces inflammation and prevents acne from appearing.
  • Clogged Pores: Isotretinoin decreases oil production and boosts the renewal of skin cells, ensuring pores stay open. This severe acne treatment prevents dead skin cells and sebum from accumulating, which can cause blackheads and whiteheads.
  • Inflammation: Isotretinoin offers anti-inflammatory benefits that calm irritated skin and diminish the redness and swelling that come with acne.


Isotretinoin is a strong medication. It's a very effective severe acne treatment for our Papillion clients but requires careful monitoring because of its side effects. Unlike other acne treatments, isotretinoin requires doctors to closely monitor patients and might lead to changes in how patients live their daily lives. Here’s what to expect:

  • Monthly Dermatologist Appointments: It’s important to see your dermatologist once a month and have monthly blood work to monitor blood count, liver function, and fasting lipids.
  • Strict Monitoring: Isotretinoin usage is subject to strict monitoring due to its risk of causing birth defects and other side effects. Women of childbearing potential are required to undergo regular pregnancy tests, use two forms of birth control, and enroll in the iPLEDGE® program to ensure the drug is used responsibly.
  • Enhanced Sun Protection: Due to increased sensitivity to sunlight caused by isotretinoin, adopting enhanced sun protection measures is essential. This includes applying broad-spectrum sunscreen with an SPF of 30 or higher, wearing protective clothing, and minimizing exposure during peak sunlight hours.
  • Potential for Dryness: A common side effect of isotretinoin treatment is dryness, affecting the lips, skin, and mucous membranes. Patients are advised to modify their skincare routines by incorporating more intensive moisturizers and lip balms to alleviate dryness.
  • Lifestyle Adjustments: The fragility of the skin while on isotretinoin necessitates adjustments in activities such as waxing, laser skin treatments, and heavy exercise. Consulting with a dermatologist allows for the identification of necessary changes to safely continue these activities.
  • Mental Health Awareness: Given the ongoing research into isotretinoin's potential impact on mental health, particularly its possible link to depression, healthcare providers are vigilant in monitoring patients for mood changes. Recommendations for additional mental health support may be made if concerns arise.
  • Blood Donation Restrictions: Individuals taking isotretinoin are advised against donating blood during treatment and for a specified period afterward due to potential impacts on blood cell counts. This restriction ensures both donor safety and the integrity of the blood supply.

In your first appointment at our clinic, we will carefully explain all the safety aspects of your acne medication plan. Our Papillion-area dermatologists are here to clear up any questions or concerns you might have, aiming to make you feel completely informed and comfortable before starting your treatment.


Clear skin can boost your confidence, and isotretinoin acne treatment allows our Papillion clients to combat severe acne. However, we also offer other treatment options. Schedule your appointment today to discuss whether isotretinoin or another treatment option is best for you.