When you have severe acne, especially the cystic or nodular kind, it can be tough to get rid of using the usual topical and oral acne medications. Sometimes, these common treatments don't work well enough. That's when our dermatologists might suggest isotretinoin, a special prescription medication made for severe acne.

Isotretinoin can help clear up acne for an extended time and maybe even permanently. At MOD Dermatology, we offer isotretinoin acne treatment. Our Gretna-area dermatologists will talk with you about what you're experiencing, how to use this medicine the right way, and what side effects it might have.

What is Isotretinoin?

Isotretinoin is an oral medication and requires a prescription to obtain. It's unique because it targets the four main acne triggers: too much oil production, bacteria P. acnes, blocked pores, and inflammation. Understanding these causes helps explain why this treatment is so effective.


Your body makes an oil called sebum to keep your hair and skin moist. Sometimes, it makes too much of this oil, and skin cells get stuck in your pores. When these clogged pores trap the bacteria present on the skin, it leads to inflammation. This is usually how acne starts. Isotretinoin, offered by our dermatologists near Gretna, is a severe acne treatment that addresses these problems, including:

  • Excess Sebum Production: Isotretinoin makes the oil glands smaller, which lowers the amount of oil the skin makes. This action helps stop pores from getting blocked and stops acne from forming.
  • Bacteria P. Acne: Isotretinoin works to control bacteria, which are major players in causing acne. By cutting down on bacteria, isotretinoin reduces inflammation and prevents new acne from developing.
  • Clogged Pores: Isotretinoin reduces oil production and helps skin cells renew faster, keeping pores unclogged. This action prevents dead skin and oil from mixing and creating blackheads and whiteheads.
  • Inflammation: Isotretinoin has qualities that calm irritated skin and lessen the redness and puffiness that come with acne.


Isotretinoin is a potent drug used in severe acne treatment. It's much stronger than usual acne remedies and demands strict safety measures because of its side effects. Unlike simpler acne treatments, isotretinoin at our Bellevue-area clinic necessitates close monitoring by doctors and possible lifestyle changes for patients. Here's what to expect:

  • Monthly Dermatology Appointments: You’ll need to visit your dermatologist on a monthly basis and have blood work to monitor fasting lipids, liver function, and blood count.
  • Strict Monitoring: Because isotretinoin can lead to severe birth defects and other adverse effects, its use is tightly controlled. Women of childbearing potential must use two forms of birth control, take pregnancy tests, and engage the iPLEDGE® program to guarantee the medication's safe use.
  • Enhanced Sun Protection: Isotretinoin heightens sun sensitivity, necessitating a strict sun protection routine. This includes using sunscreen with a minimum SPF of 30, wearing sun-protective clothing, and limiting exposure during peak sunlight hours.
  • Potential for Dryness: Isotretinoin frequently results in dryness, affecting the lips, skin, and mucous membranes. To combat this, patients may need to introduce heavy-duty moisturizers and lip balms into their skincare regimen.
  • Lifestyle Adjustments: The treatment may require changes to certain activities such as waxing, undergoing laser procedures, or engaging in vigorous exercise due to increased skin sensitivity. Effective communication with a dermatologist is essential to navigate these adjustments.
  • Mental Health Awareness: Ongoing studies are examining the potential link between isotretinoin and depression. Physicians monitor patients for mood alterations and might suggest additional mental health support when necessary.
  • Blood Donation Restrictions: Isotretinoin users are discouraged from donating blood because of its possible impact on blood cell counts. This prohibition extends for at least 30 days after the completion of treatment.

During your first visit, our clinic will thoroughly explain what to expect with your acne medication. Our Gretna-area dermatologists are here to address any questions or concerns you have, ensuring you feel well-informed and at ease before starting your treatment.


Clear skin and boosted confidence are within reach with the right severe acne treatment. Isotretinoin is a powerful option, but it's not the only solution. At MOD Dermatology, we understand how challenging acne can be and offer various treatments tailored to meet your specific needs. Call today to schedule your appointment!